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The researchers found that the risk of myocarditis in young men was higher than expected after full vaccination.

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The researchers found that the risk of myocarditis in young men was higher than expected after full vaccination.

Men aged 16 to 29 have an increased risk of developing heart problems after receiving a second dose of coronavirus vaccines made by Pfizer-BioNtech or Moderna, according to a large new analysis published Wednesday in the New England Journal of Medicine. goes.

The study in Israel estimated that about 11 out of every 100,000 men in that age group developed myocarditis, an inflammation of the heart, a few days after being fully vaccinated. This figure is higher than earlier estimates.

According to a second study in the journal Myocarditis, the incidence of myocarditis was highest in boys aged 16 to 19 years after the second dose. The risk of heart problems among boys of that age was nine times higher than that of boys of the same age.

The absolute risk is still very small, and the situation is temporary. And studies have shown that COVID-19 is more likely to cause heart problems than vaccination.

Based on data available in June, advisers from the Centers for Disease Control and Prevention unanimously voted to recommend the vaccine, saying the benefits far outweigh the risks. The agency has estimated that for every one million boys ages 12 to 17, the shots could cause a maximum of 70 myocarditis cases, but would prevent 5,700 infections, 215 hospitalizations, and two deaths.

Myocarditis is one of the concerns that led the Food and Drug Administration to ask Pfizer-BioNtech and Moderna to enroll more children in their vaccine trials. Potential side effects are likely to dominate discussion at next week’s meeting of the agency’s advisors to review the vaccine evidence in children aged 5 to 11.

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One of the new studies looked at data from 2.5 million immunized members of Israel’s largest health care network, who were 16 years of age or older. Researchers identified 54 cases of myocarditis, and 41 of them were considered mild. About 70 percent of myocarditis cases were observed after the second dose.

One case was so severe that ventilation was required. One patient with a history of heart disease died of unknown cause soon after being discharged from the hospital. Of the 14 patients who showed cardiac abnormalities during hospitalization, 10 still had symptoms of some problems when they were discharged.

But when the patients were examined again a few weeks later, all five of them for whom the results were available made a full recovery.

The study found that across all age groups and genders, the overall incidence was just two cases per 100,000 people. But when the researchers analyzed the results by age and gender, they found the highest incidence among men ages 16 to 29. The risk was negligible in women of all ages.

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