Stem cell research community not entitled to 14-day limit on human embryo testing – stem cell research community not entitled to 14-day limit on human embryo testing

Stem cell research community not entitled to 14-day limit on human embryo testing – stem cell research community not entitled to 14-day limit on human embryo testing

Halifax (Canada), May 28 (The Conversation) The International Society for Stem Cell Research (ISSCR), an organization that describes itself as the “voice of the stem cell research community”, has announced that it will be conducting research on human embryonic research. No longer supports the prevailing international standard limiting gestation to 14 days after fertilization.

The issue of human embryo research has long been a stinging topic as conflicting views have been expressed about the ethical status of the developing embryo. Some argue that human embryos have an ethical nature of life and are considered consensual human life – that embryos should not be used for research, especially research that involves their destruction.

Others reject such claims and mention the potential scientific and therapeutic benefits associated with the research of human embryos. These benefits include screening for human development, cancer cell growth, congenital disease, and abortion. Based on this research, development of contraceptives, diagnosis of genetic diseases, treatment of infertility and other pathologies are included.

Pre-2016 ISSCR guidelines prohibit the extraction and use of embryos over 14 days old for research. The updated guidelines announced on 26 May do away with this restriction. Instead, ISSCR recommends that “national academies of science, educational societies, moneylenders and regulators” engage the public in discussions about scientific, social, and ethical issues associated with the 14-day limit, and whether this The range should be extended based on the objectives of the research.

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History of the 14 Day Rule

The 14-day rule, also known as the 14-day limit, “became a standard part of embryo-research inspection based on the deliberations of various national committees over the decades.”

Today, different countries have more or less different rules regarding the moral status of the human fetus, considering any one of them to be true. Some countries – such as Austria, Germany, Italy, Russia and Turkey – do not allow research involving human embryos.

Other countries – including Canada, China, India, Japan, Spain and the UK – allow limited research of human embryos for up to 14 days (and not beyond). There are also some countries that allow such research without setting any kind of time limit, these include Brazil and France.

In 1979, after extensive public consultation, the Ethics Advisory Board of the US Department of Health, Education, and Welfare released a report in support of limited human fetal research. The board concluded that research involving human embryos should be allowed, provided the embryo is “not in vitro beyond the stage that is normally associated with completion of implantation (14 days after fertilization).”

Five years later, after extensive public consultation, the Warnock Report of the Committee on Investigation into Human Fertilization and Embryology in Britain also reached a similar conclusion. However, a different biological process was premised in this report was the presence of primitive streaks (indicative of brain and spinal cord composition) in the embryonic structure, which appears on the 14th or 15th day of fertilization.

The first national legislation to strengthen the proposed ethical limit of 14 days was introduced in the UK in the Human Fertilization and Embryology Act of 1990. Since then other countries (but not the US) have followed suit and introduced similar laws.

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In Canada, the Assisted Human Reproduction Act of 2004 stipulates that no person will “intentionally keep a fetus out of a woman’s body after fertilization or the 14th day of its development after creation, not including the time.” , In which the development of the fetus is suspended. ”

Till now, the ISSCR guidelines were in line with the laws, regulations and guidelines supporting the 14-day limit, but no more.

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